Week 2- Day 4 Bioinformatics Test.

Science meets Art-beautiful work outside the UCD science block!

Science meets Art-beautiful work outside the UCD science block!

We have spent the last 3 days learning about sequencing, alignment, creating trees, the algorithms and the role of probability in the program’s used to create the trees and to grade their reliability.

So basically maths is vital to the creation of the trees.

Last day with Graham and without any help we have to Search the database for a sequence of choice, BLAST the sequence and select organisms with listed that match somewhat our target.

MEGA- model analysis tool, MEGA is giving the best MODEL to create your tree with

MEGA- model analysis tool, MEGA is giving the best MODEL to create your tree with

We align the sequences using Clustal, import the alignment into MEGA(programme that will create the tree), select the model that will create the most mathematically reliable model and create the tree.

Phylogenetic Tree-Alpacas, Camels and Platypus

Phylogenetic Tree-Alpacas, Camels and Platypus

All managed thanks to Graham’s teaching skills!

We also checked out Chimera and viewed 3D model images of proteins we had BLASTED-Cytochrome b and opsin ( red and green colour receptor).

Cytochrome b

Cytochrome b

image

 

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